Search results for "Eslicarbazepine acetate"

showing 1 items of 1 documents

Effectiveness of eslicarbazepine acetate in dependency of baseline anticonvulsant therapy: Results from a German prospective multicenter clinical pra…

2019

Abstract Eslicarbazepine acetate (ESL) is a third-generation antiepileptic drug (AED) approved as monotherapy for partial-onset seizures in adults and as adjunctive therapy in patients aged above 6 years in the European Union (EU). The prospective observational Zebinix Effects in DEpendency of BAseline Conditions (ZEDEBAC) study aimed at investigating the effectiveness of ESL in clinical practice, with ESL being administered as monotherapy (mono group), as only add-on to a current monotherapy (1 + group), or as add-on to ≥ 2 baseline AEDs (≥ 2 + group). In total, 237 patients were included, 35 in the mono group, 114 in the 1 +, and 88 in the ≥ 2 + group. Six-month retention rates were 93.9%…

AdultMaleDrug Resistant Epilepsymedicine.medical_specialtyYoung Adult03 medical and health sciencesBehavioral NeuroscienceEpilepsy0302 clinical medicineSodium channel blockerRefractoryDibenzazepinesSeizuresInternal medicineHumansMedicinemedia_common.cataloged_instanceProspective Studies030212 general & internal medicineEuropean unionAgedmedia_commonbusiness.industryMiddle Agedmedicine.diseaseNeurologyEslicarbazepine acetateConcomitantAnticonvulsantsFemaleObservational studyNeurology (clinical)businessHyponatremia030217 neurology & neurosurgerySodium Channel Blockersmedicine.drugEpilepsy & Behavior
researchProduct